Wound Care Certified Certification (WCC) Practice Exam

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What is the etiology of calciphylaxis?

Excessive iron deposits
Excessive calcium deposits in the microvascular system
Vitamin D deficiency
Hyperparathyroidism

The correct answer is: Excessive calcium deposits in the microvascular system

Calciphylaxis is primarily characterized by excessive calcium deposits in the small blood vessels (microvasculature) of the skin and adipose tissue. This condition often occurs in patients with chronic kidney disease, particularly those on dialysis, where disturbances in calcium and phosphorus metabolism lead to vascular calcification. The resultant calcific deposits can obstruct blood flow, leading to ischemia and necrosis of the skin tissues. Understanding this etiology is critical in clinical practice, as the management of calciphylaxis focuses on addressing the underlying disorders and avoiding factors that could exacerbate the condition, such as dysregulation of calcium and phosphate levels. The other options may relate to bone metabolism or systemic conditions but do not directly address the pathological process specific to calciphylaxis.