Wound Care Certified Certification (WCC) Practice Exam

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What topical antimicrobial agent is used to prevent and treat wound sepsis in burns?

  1. Cadexomer iodine

  2. Honey ointment

  3. Silver sulfadiazine

  4. Chlorhexidine

The correct answer is: Silver sulfadiazine

Silver sulfadiazine is a topical antimicrobial agent widely used in the management of burns to prevent and treat wound sepsis. Its effectiveness comes from its broad-spectrum antimicrobial properties, which are crucial in preventing infection in burn injuries that have compromised the skin barrier. This agent works by releasing silver ions, which have been shown to disrupt bacterial cell walls and inhibit their growth. This function is particularly important for burn wounds because they are susceptible to infections due to exposure, loss of skin integrity, and always being in a moist environment, which is conducive for bacterial proliferation. Moreover, silver sulfadiazine has additional benefits, such as promoting wound healing and providing a soothing effect on the burn area, which can help manage pain and discomfort associated with the injury. Its effectiveness and safety profile make it a standard choice in clinical practice for the treatment of burns. In contrast to the other agents listed, while they may have their place in wound care, none have the specific combination of broad antimicrobial action and burn wound appropriateness that silver sulfadiazine offers.